XB-ART-7293
Br J Pharmacol
2002 Apr 01;1358:1977-87. doi: 10.1038/sj.bjp.0704651.
Show Gene links
Show Anatomy links
The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro.
Coyne L
,
Lees G
,
Nicholson RA
,
Zheng J
,
Neufield KD
.
???displayArticle.abstract???
???displayArticle.pubmedLink??? 11959801
???displayArticle.pmcLink??? PMC1573315
???displayArticle.link??? Br J Pharmacol
References [+] :
Basile,
Characterization of the hypnotic properties of oleamide.
1999, Pubmed
Basile, Characterization of the hypnotic properties of oleamide. 1999, Pubmed
Beaumont, Muscimol binding in rat brain: association with synaptic GABA receptors. 1978, Pubmed
Belelli, General anaesthetic action at transmitter-gated inhibitory amino acid receptors. 1999, Pubmed
Belelli, The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid. 1997, Pubmed , Xenbase
Belelli, The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors. 1999, Pubmed , Xenbase
Bloomquist, Inhibition of gamma-aminobutyric acid-stimulated chloride flux in mouse brain vesicles by polychlorocycloalkane and pyrethroid insecticides. 1986, Pubmed
Boger, Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide. 1998, Pubmed
Boger, Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. 1998, Pubmed
Boring, Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. 1996, Pubmed
Cheer, Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors. 1999, Pubmed
Cravatt, Chemical characterization of a family of brain lipids that induce sleep. 1995, Pubmed
DeLorey, Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acidA receptor in rat cerebral cortical synaptoneurosomes. 1993, Pubmed
Edwards, Modulation of a recombinant invertebrate gamma-aminobutyric acid receptor-chloride channel complex by isoflurane: effects of a point mutation in the M2 domain. 1997, Pubmed , Xenbase
Franks, Molecular and cellular mechanisms of general anaesthesia. 1994, Pubmed
Gobbi, Oleamide-mediated sleep induction does not depend on perturbation of membrane homeoviscosity. 1999, Pubmed
Goodnough, Neuroactive steroid modulation of [3H]muscimol binding to the GABAA receptor complex in rat cortex. 1995, Pubmed
Halliwell, Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid. 1999, Pubmed , Xenbase
Hanus, A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids. 1999, Pubmed
Harris, Functional coupling of gamma-aminobutyric acid receptors to chloride channels in brain membranes. 1985, Pubmed
Harris, Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors. 1994, Pubmed
Huang, Characterization of [3H]ethynylbicycloorthobenzoate ([3H]EBOB) binding and the action of insecticides on the gamma-aminobutyric acid-gated chloride channel in cultured cerebellar granule neurons. 1996, Pubmed
Huidobro-Toro, Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. 1996, Pubmed , Xenbase
Ito, Studies on picrotoxin binding sites of GABAA receptors in rat cortical synaptoneurosomes. 1994, Pubmed
Itouji, Neuronal and glial localization of two GABA transporters (GAT1 and GAT3) in the rat cerebellum. 1996, Pubmed
Iversen, The uptake of [3H]GABA by slices of rat cerebral cortex. 1968, Pubmed
Koenig, Effect of free fatty acids on GABAA receptor ligand binding. 1992, Pubmed
Koltchine, Chimeric GABAA/glycine receptors: expression and barbiturate pharmacology. 1996, Pubmed
Krasowski, The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations. 2000, Pubmed , Xenbase
Lawrence, t-[3H]butylbicycloorthobenzoate: new radioligand probe for the gamma-aminobutyric acid-regulated chloride ionophore. 1985, Pubmed
Laws, Fatty acid amides are putative endogenous ligands for anaesthetic recognition sites in mammalian CNS. 2001, Pubmed
Lees, Modulation of GABA(A) receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis-9,10-octadecenoamide (cOA). 1998, Pubmed , Xenbase
Lerner, A hypothesis about the endogenous analogue of general anesthesia. 1997, Pubmed
Martin, Ions and the transport of gamma-aminobutyric acid by synaptosomes. 1972, Pubmed
Mehta, An update on GABAA receptors. 1999, Pubmed
Mendelson, The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist. 1999, Pubmed
Mihic, Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. 1997, Pubmed , Xenbase
Negro, Effect of ethanol treatment on rate and equilibrium constants for [3H] muscimol binding to rat brain membranes: alteration of two affinity states of the GABAA receptor. 1995, Pubmed
Nicholson, Anesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain. 2001, Pubmed
Nicholson, Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain. 1999, Pubmed
Pascoe, Drugs and the sleep-wakefulness continuum. 1994, Pubmed
Peterson, A simplification of the protein assay method of Lowry et al. which is more generally applicable. 1977, Pubmed
Ramanjaneyulu, Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site. 1984, Pubmed
Sakurai, Quantitative autoradiography of [3H]t-butylbicycloorthobenzoate binding to the gamma-aminobutyric acid receptorA complex. 1994, Pubmed
Soja, The postsynaptic inhibitory control of lumbar motoneurons during the atonia of active sleep: effect of strychnine on motoneuron properties. 1991, Pubmed
Squires, [35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites. 1983, Pubmed
Tecott, Designer genes and anti-anxiety drugs. 2000, Pubmed
Thompson, Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination. 1996, Pubmed , Xenbase
Thomsen, 1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter. 1997, Pubmed
Turner, Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates. 1989, Pubmed
Verdon, Stereoselective modulatory actions of oleamide on GABA(A) receptors and voltage-gated Na(+) channels in vitro: a putative endogenous ligand for depressant drug sites in CNS. 2000, Pubmed
Wafford, Ethanol sensitivity of the GABAA receptor expressed in Xenopus oocytes requires 8 amino acids contained in the gamma 2L subunit. 1991, Pubmed , Xenbase
Wafford, A novel allosteric modulatory site on the GABAA receptor beta subunit. 1994, Pubmed , Xenbase
Wilson, Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. 2001, Pubmed
Yost, Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration. 1998, Pubmed , Xenbase