XB-ART-6284
Dev Cell
2002 Oct 01;34:465-7. doi: 10.1016/s1534-5807(02)00294-0.
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The (theoretical) yin and yang of spindle mechanics.
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Antiparallel overlap of microtubules is central to the morphogenesis of bipolar mitotic spindles. How does this overlap arise, and how is it maintained? A recent theoretical study uses computer simulations to investigate whether motor protein complexes can achieve this task. The "virtual" results reveal that a mixed polarity motor complex is needed to do the job.
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