Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-60104
Dev Growth Differ 1985 Jan 01;273:283-294. doi: 10.1111/j.1440-169X.1985.00283.x.
Show Gene links Show Anatomy links

Energy Metabolism and Pyridine Nucleotide Levels during Xenopus Oocyte Maturation*, 1 : (xenopus oocytes/pyridine nucleotides/energy metabolism/meiotic cell division).

Cicirelli MF , Smith LD .


???displayArticle.abstract???
The rate of oxygen consumption increased in maturing Xenopus oocytes within 2 hr after progesterone addition, well before GVBD. This suggested an early requirement for energy metabolism during maturation, similar to the situation in sea urchin eggs during fertilization. Yet, the absence of similar increases in glucose-6-phosphate levels, glucose-6-phosphate dehydrogenase activity, glucose conversion to CO2 , and the conversion of NAD(H) to NADP(H), indicated that carbohydrate metabolism was not being stimulated in Xenopus oocytes during maturation. The oxidation of other energy yielding substrates is discussed which might account for the finding that, within 5 min of progesterone addition, both reduced forms of the pyridine nucleotides increased 20% over control levels. This was later followed by a drop in NADH levels and a rise in NAD relative to controls. The significance of these changes in pyridine nucleotide levels and their relationship to a number of maturation events are discussed.

???displayArticle.pubmedLink??? 37281816
???displayArticle.link??? Dev Growth Differ