Kollewe A , Chubanov V , Tseung FT , Correia L , Schmidt E , Rössig A , Zierler S , Haupt A , Müller CS , Bildl W , Schulte U , Nicke A , Fakler B , Gudermann T .

TRR 152 P15 Deutsche Forschungsgemeinschaft, TRR 152 P02 Deutsche Forschungsgemeinschaft, SFB 1328 P15 Deutsche Forschungsgemeinschaft, SFB 1381 Deutsche Forschungsgemeinschaft, Research Training Group 2338 Deutsche Forschungsgemeinschaft, TRR 152 P14 Deutsche Forschungsgemeinschaft

             zinc ion homeostasis

Aarts, A key role for TRPM7 channels in anoxic neuronal death. 2003, Pubmed

Aarts, A key role for TRPM7 channels in anoxic neuronal death. 2003, Pubmed
Abiria, TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles. 2017, Pubmed
Arjona, CrossTalk opposing view: CNNM proteins are not Na+ /Mg2+ exchangers but Mg2+ transport regulators playing a central role in transepithelial Mg2+ (re)absorption. 2018, Pubmed
Bildl, Extending the dynamic range of label-free mass spectrometric quantification of affinity purifications. 2012, Pubmed
Cai, Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases. 2017, Pubmed
Chambers, A cross-platform toolkit for mass spectrometry and proteomics. 2012, Pubmed
Chen, Crystal structure of an archaeal CorB magnesium transporter. 2021, Pubmed
Chubanov, Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. 2004, Pubmed , Xenbase
Chubanov, TRPM6. 2014, Pubmed
Chubanov, Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. 2016, Pubmed
Chubanov, Role of kinase-coupled TRP channels in mineral homeostasis. 2018, Pubmed
Clark, The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC. 2008, Pubmed
Corre, Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes. 2018, Pubmed
Desai, Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. 2012, Pubmed
Dorovkov, Phosphorylation of annexin I by TRPM7 channel-kinase. 2004, Pubmed
Duan, Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. 2018, Pubmed
Faouzi, The TRPM7 channel kinase regulates store-operated calcium entry. 2017, Pubmed
Ferioli, TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP. 2017, Pubmed
Fleig, TRPM7. 2014, Pubmed , Xenbase
Funato, Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression. 2014, Pubmed
Funato, Molecular function and biological importance of CNNM family Mg2+ transporters. 2019, Pubmed
Gillingham, The small G proteins of the Arf family and their regulators. 2007, Pubmed
Giménez-Mascarell, Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2. 2017, Pubmed
Giménez-Mascarell, Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators. 2019, Pubmed
Gloor, A vector for the synthesis of cRNAs encoding Myc epitope-tagged proteins in Xenopus laevis oocytes. 1995, Pubmed , Xenbase
Gulerez, Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis. 2016, Pubmed
Hardy, The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis. 2015, Pubmed
Hayes, Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. 2000, Pubmed , Xenbase
Hermosura, A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders. 2005, Pubmed
Heukeshoven, Improved silver staining procedure for fast staining in PhastSystem Development Unit. I. Staining of sodium dodecyl sulfate gels. 1988, Pubmed
Hofmann, Activation of TRPM7 channels by small molecules under physiological conditions. 2014, Pubmed
Huang, Structural basis for the Mg2+ recognition and regulation of the CorC Mg2+ transporter. 2021, Pubmed
Huttlin, A tissue-specific atlas of mouse protein phosphorylation and expression. 2010, Pubmed
Huttlin, Architecture of the human interactome defines protein communities and disease networks. 2017, Pubmed
Huttlin, Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. 2021, Pubmed
Jin, Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. 2008, Pubmed
Jin, The channel kinase, TRPM7, is required for early embryonic development. 2012, Pubmed
Kostantin, Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth. 2016, Pubmed
Krapivinsky, The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase. 2014, Pubmed
Liu, TRPM7 Is Required for Normal Synapse Density, Learning, and Memory at Different Developmental Stages. 2018, Pubmed
Mederos y Schnitzler, Evolutionary determinants of divergent calcium selectivity of TRPM channels. 2008, Pubmed
Mittermeier, TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival. 2019, Pubmed
Monteilh-Zoller, TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. 2003, Pubmed
Müller, Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. 2010, Pubmed
Müller, Cryo-slicing Blue Native-Mass Spectrometry (csBN-MS), a Novel Technology for High Resolution Complexome Profiling. 2016, Pubmed
Müller, High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis. 2019, Pubmed
Nadler, LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. 2001, Pubmed
Nguyen, Investigating Phosphorylation Patterns of the Ion Channel TRPM7 Using Multiple Extraction and Enrichment Techniques Reveals New Phosphosites. 2019, Pubmed
Pandey, Proteomics to study genes and genomes. 2000, Pubmed
Parry, Mutations in CNNM4 cause Jalili syndrome, consisting of autosomal-recessive cone-rod dystrophy and amelogenesis imperfecta. 2009, Pubmed
Perraud, The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. 2011, Pubmed
Richards, A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. 2009, Pubmed
Rivera, Constitutive Phosphorylation as a Key Regulator of TRPM8 Channel Function. 2021, Pubmed
Romagnani, TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut. 2017, Pubmed
Runnels, TRP-PLIK, a bifunctional protein with kinase and ion channel activities. 2001, Pubmed
Runnels, The TRPM7 channel is inactivated by PIP(2) hydrolysis. 2002, Pubmed
Ryazanov, Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase. 1997, Pubmed
Sah, Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. 2013, Pubmed
Sah, Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. 2013, Pubmed
Schmidt, Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance. 2017, Pubmed
Schmitz, Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. 2003, Pubmed
Schwenk, Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. 2010, Pubmed , Xenbase
Schwenk, High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. 2012, Pubmed , Xenbase
Schwenk, Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics. 2016, Pubmed
Schägger, Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. 2000, Pubmed
Song, Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion. 2017, Pubmed
Stritt, Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. 2016, Pubmed
Stuiver, CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia. 2011, Pubmed
Sun, Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. 2009, Pubmed
Voringer, Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity. 2020, Pubmed
Yamazaki, Basolateral Mg2+ extrusion via CNNM4 mediates transcellular Mg2+ transport across epithelia: a mouse model. 2013, Pubmed
Zhang, PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3. 2017, Pubmed
Zhou, Toward a comprehensive characterization of a human cancer cell phosphoproteome. 2013, Pubmed