Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Wilehm Roux Arch Dev Biol
1983 May 01;1923-4:130-137. doi: 10.1007/BF00848681.
Show Gene links
Show Anatomy links
Change in the differentiation pattern ofXenopus laevis ectoderm by variation of the incubation time and concentration of vegetalizing factor.
Grunz H
.
???displayArticle.abstract???
Early amphibian gastrulaectoderm (Xenopus laevis) has been treated with vegetalizing factor using the sandwich technique, varying the period of incubation and the inducer concentration.The pattern of induced tissues depends on three factors: the inducer concentration, the size of inducer pellet and the time of exposure of ectodermal target cells to inducer.Short treatment with inducer will result in the formation of blood cells and heart structures. An increase in incubation time or inducer concentration, or both, will cause the formation of increasing amounts of such dorsal mesodermal structures as pronephros, somites and notochord. Neural structures can only be observed in explants with considerable amounts of somites and notochord.Ectoderm treated with high concentrations of vegetalizing factor for the whole period of competence will differentiate into endoderm.Furthermore, the results show thatX. laevis ectoderm does not show any autoneuralizing tendency under our experimental conditions. It therefore seems to be a suitable tool for the study of primary embryonic induction.
Asahi,
Formation of mesodermal pattern by secondary inducing interactions.
1979, Pubmed
Asahi,
Formation of mesodermal pattern by secondary inducing interactions.
1979,
Pubmed
Asashima,
Inducing effects of the presumptive endoderm of successive stages inTriturus alpestris.
1975,
Pubmed
Born,
Isolation of a vegetalizing inducing factor.
1972,
Pubmed
Born,
Biological activity of the vegetalizing factor: Decrease after coupling to polysaccharide matrix and enzymatic recovery of active factor.
1980,
Pubmed
Boterenbrood,
The formation of the mesoderm in urodelean amphibians : V. Its regional induction by the endoderm.
1973,
Pubmed
Geithe,
Isolation of a homogeneous morphogenetic factor, inducing mesoderm and endoderm derived tissues in Triturus ectoderm.
1975,
Pubmed
Grunz,
[Influence of inhibitors of RNA and protein synthesis and inductors upon cell affinity of amphibian tissues].
1972,
Pubmed
Grunz,
[Relationship between competence and protein synthesis in amphibian ectoderm].
1970,
Pubmed
Grunz,
Change of the differentiation pattern of amphibian ectoderm after the increase of the initial cell mass.
1979,
Pubmed
Holtfreter,
[Not Available].
1933,
Pubmed
Kocher-Becker,
Induction of mesodermal and endodermal structures and primordial germ cells in Triturus ectoderm by a vegetalizing factor from chick embryos.
1971,
Pubmed
Leikola,
On the loss of mesodermal competence of the Triturus gastrula ectoderm in vivo.
1965,
Pubmed
Minuth,
The formation of mesodermal derivatives after induction with vegetalizing factor depends on secondary cell interactions.
1980,
Pubmed
Nieuwkoop,
The Formation of the Mesoderm in Urodelean Amphibians : II. The origin of the dorso-ventral polarity of the mesoderm.
1969,
Pubmed
Okada,
Epithelio-mesenchymal relationships in the regional differentiation of the digestive tract in the amphibian embryo.
1960,
Pubmed
Tiedemann,
Biological activity of vegetalizing and neuralizing inducing factors after binding to BAC-cellulose and CNBr-sepharose.
1978,
Pubmed
