Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Rouxs Arch Dev Biol
1991 Jun 01;2001:51-57. doi: 10.1007/BF02457641.
Show Gene links
Show Anatomy links
The involvement of mitochondria in carbon metabolism in cleavingXenopus embryos.
Dworkin MB
,
Dworkin-Rastl E
.
???displayArticle.abstract???
The major carbon sources inXenopus oocytes and cleavage-stage embryos appear to be amino acids, which are oxidized to form pyruvate (to support the Krebs cycle) and phosphoenolpyruvate (for anabolic processes). Metabolism of various metabolites in vitro into aspartate or glutamate, and then partially into phosphoenolpyruvate, requires the presence of mitochondria, suggesting that metabolism in vivo utilizes mitochondrial enzymes. The rate limiting step in metabolism in the stage VI oocyte appears to be uptake and/or metabolism of compounds by the mitochondria; the rate of metabolism increases during maturation. During early cleavage no qualitative differences in metabolism were observed either as a function of development, or spatially along the animal/vegetal or prospective dorsal/ventral axes.
Black,
Experimental reversal of the normal dorsal-ventral timing of blastopore formation does not reverse axis polarity in Xenopus laevis embryos.
1989, Pubmed,
Xenbase
Black,
Experimental reversal of the normal dorsal-ventral timing of blastopore formation does not reverse axis polarity in Xenopus laevis embryos.
1989,
Pubmed
,
Xenbase
Dworkin,
Regulation of carbon flux from amino acids into sugar phosphates in Xenopus embryos.
1990,
Pubmed
,
Xenbase
Dworkin,
Metabolic regulation during early frog development: glycogenic flux in Xenopus oocytes, eggs, and embryos.
1989,
Pubmed
,
Xenbase
Eppig,
Amino acid pools in developing oocytes of Xenopus laevis.
1972,
Pubmed
,
Xenbase
Halestrap,
Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate.
1974,
Pubmed
Kao,
Lithium-induced respecification of pattern in Xenopus laevis embryos.
,
Pubmed
,
Xenbase
Løvtrup-Rein,
Changes in energy metabolism during the early development of Xenopus laevis.
1982,
Pubmed
,
Xenbase
Salomon de Legname,
Biochemical studies on the energetics of Bufo arenarum segmenting éggs.
1969,
Pubmed
Salomón de Legname,
Source of precursors for nucleotide biosynthesis in Bufo arenarum segmenting eggs.
1975,
Pubmed
Taylor,
Accumulation of free amino acids in growing Xenopus laevis oocytes.
1987,
Pubmed
,
Xenbase
Thoman,
Absence of dorsal-ventral differences in energy metabolism in early embryos of Xenopus laevis.
1979,
Pubmed
,
Xenbase
Vincent,
Kinematics of gray crescent formation in Xenopus eggs: the displacement of subcortical cytoplasm relative to the egg surface.
1986,
Pubmed
,
Xenbase