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Figure 1. Two mechanisms for contraction: buckling and end clustering.Top: When two anti-parallel actin filaments are bridged by a myosin motor (blue) and a crosslink (green), their relative movement forces one filament to buckle, resulting in the contraction of the network. Bottom: Microtubule contraction seems to depend on the affinity of dynein motors (red) for the ends of the filaments. For a recent review on the topic of contraction, see Clark et al., 2014.
Clark,
Stresses at the cell surface during animal cell morphogenesis.
2014, Pubmed
Clark,
Stresses at the cell surface during animal cell morphogenesis.
2014,
Pubmed
Foster,
Active contraction of microtubule networks.
2015,
Pubmed
,
Xenbase
Hentrich,
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14.
2010,
Pubmed
,
Xenbase
Lenz,
Contractile units in disordered actomyosin bundles arise from F-actin buckling.
2012,
Pubmed
Sawin,
Mitotic spindle assembly by two different pathways in vitro.
1991,
Pubmed
,
Xenbase
