XB-ART-48219
Cell Stem Cell
2012 Dec 07;116:748-50. doi: 10.1016/j.stem.2012.11.014.
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Cellular reprogramming in pursuit of immortality.
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The discovery that phenotypic diversity among differentiated cells results from epigenetic and not genetic differences, and can be reset to restore pluripotency, promises revolutionary advances in medicine. I discuss how this and related seminal discoveries have brought us to an exciting future.
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