Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Plant Cell Physiol
2014 Jan 01;551:148-61. doi: 10.1093/pcp/pct166.
Show Gene links
Show Anatomy links
The Thellungiella salsuginea tonoplast aquaporin TsTIP1;2 functions in protection against multiple abiotic stresses.
Wang LL
,
Chen AP
,
Zhong NQ
,
Liu N
,
Wu XM
,
Wang F
,
Yang CL
,
Romero MF
,
Xia GX
.
???displayArticle.abstract???
Examination of aquaporin (AQP) membrane channels in extremophile plants may increase our understanding of plant tolerance to high salt, drought or other conditions. Here, we cloned a tonoplast AQP gene (TsTIP1;2) from the halophyte Thellungiella salsuginea and characterized its biological functions. TsTIP1;2 transcripts accumulate to high levels in several organs, increasing in response to multiple external stimuli. Ectopic overexpression of TsTIP1;2 in Arabidopsis significantly increased plant tolerance to drought, salt and oxidative stresses. TsTIP1;2 had water channel activity when expressed in Xenopus oocytes. TsTIP1;2 was also able to conduct H₂O₂ molecules into yeast cells in response to oxidative stress. TsTIP1;2 was not permeable to Na(+) in Xenopus oocytes, but it could facilitate the entry of Na(+) ions into plant cell vacuoles by an indirect process under high-salinity conditions. Collectively, these data showed that TsTIP1;2 could mediate the conduction of both H₂O and H₂O₂ across membranes, and may act as a multifunctional contributor to survival of T. salsuginea in highly stressful habitats.
Aharon,
Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress.
2003, Pubmed
Aharon,
Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress.
2003,
Pubmed
Alexandersson,
Whole gene family expression and drought stress regulation of aquaporins.
2005,
Pubmed
Amtmann,
Learning from evolution: Thellungiella generates new knowledge on essential and critical components of abiotic stress tolerance in plants.
2009,
Pubmed
Andrews,
Subcellular localization of peroxidase in tomato fruit skin and the possible implications for the regulation of fruit growth.
2002,
Pubmed
Aroca,
Regulation of root water uptake under abiotic stress conditions.
2012,
Pubmed
Biela,
The Nicotiana tabacum plasma membrane aquaporin NtAQP1 is mercury-insensitive and permeable for glycerol.
1999,
Pubmed
,
Xenbase
Bienert,
Solanaceae XIPs are plasma membrane aquaporins that facilitate the transport of many uncharged substrates.
2011,
Pubmed
,
Xenbase
Bienert,
Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes.
2007,
Pubmed
Chen,
Functional analysis of nonsynonymous single nucleotide polymorphisms in human SLC26A9.
2012,
Pubmed
,
Xenbase
Clough,
Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.
1998,
Pubmed
Danielson,
Unexpected complexity of the aquaporin gene family in the moss Physcomitrella patens.
2008,
Pubmed
Danielson,
Phylogeny of major intrinsic proteins.
2010,
Pubmed
Dodge,
The mode of action of the bipyridylium herbicides, paraquat and diquat.
1971,
Pubmed
Dong,
A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress.
2006,
Pubmed
Dynowski,
Plant plasma membrane water channels conduct the signalling molecule H2O2.
2008,
Pubmed
Gao,
Overexpressing a putative aquaporin gene from wheat, TaNIP, enhances salt tolerance in transgenic Arabidopsis.
2010,
Pubmed
Gerbeau,
Aquaporin Nt-TIPa can account for the high permeability of tobacco cell vacuolar membrane to small neutral solutes.
1999,
Pubmed
,
Xenbase
Guo,
Expression and functional analysis of the rice plasma-membrane intrinsic protein gene family.
2006,
Pubmed
Gustavsson,
Intoxication from an accidentally ingested lead shot retained in the gastrointestinal tract.
2005,
Pubmed
Hajdukiewicz,
The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation.
1994,
Pubmed
Herbik,
The involvement of a multicopper oxidase in iron uptake by the green algae Chlamydomonas reinhardtii.
2002,
Pubmed
Hooijmaijers,
Hydrogen peroxide permeability of plasma membrane aquaporins of Arabidopsis thaliana.
2012,
Pubmed
Hu,
Overexpression of a wheat aquaporin gene, TaAQP8, enhances salt stress tolerance in transgenic tobacco.
2012,
Pubmed
,
Xenbase
Inan,
Salt cress. A halophyte and cryophyte Arabidopsis relative model system and its applicability to molecular genetic analyses of growth and development of extremophiles.
2004,
Pubmed
Jang,
Transgenic Arabidopsis and tobacco plants overexpressing an aquaporin respond differently to various abiotic stresses.
2007,
Pubmed
Jang,
Ectopic expression of a foreign aquaporin disrupts the natural expression patterns of endogenous aquaporin genes and alters plant responses to different stress conditions.
2007,
Pubmed
Johanson,
The complete set of genes encoding major intrinsic proteins in Arabidopsis provides a framework for a new nomenclature for major intrinsic proteins in plants.
2001,
Pubmed
Katsuhara,
Over-expression of a barley aquaporin increased the shoot/root ratio and raised salt sensitivity in transgenic rice plants.
2003,
Pubmed
Lee,
Overexpression of PIP2;5 aquaporin alleviates effects of low root temperature on cell hydraulic conductivity and growth in Arabidopsis.
2012,
Pubmed
Leitão,
Grapevine aquaporins: gating of a tonoplast intrinsic protein (TIP2;1) by cytosolic pH.
2012,
Pubmed
Lian,
The role of aquaporin RWC3 in drought avoidance in rice.
2004,
Pubmed
,
Xenbase
Lin,
Isolation and functional characterization of PgTIP1, a hormone-autotrophic cells-specific tonoplast aquaporin in ginseng.
2007,
Pubmed
,
Xenbase
Loqué,
Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole.
2005,
Pubmed
,
Xenbase
Ma,
Rh-PIP2;1, a rose aquaporin gene, is involved in ethylene-regulated petal expansion.
2008,
Pubmed
Ma,
A silicon transporter in rice.
2006,
Pubmed
Maurel,
The vacuolar membrane protein gamma-TIP creates water specific channels in Xenopus oocytes.
1993,
Pubmed
,
Xenbase
Maurel,
Plant aquaporins: membrane channels with multiple integrated functions.
2008,
Pubmed
Maurel,
The cellular dynamics of plant aquaporin expression and functions.
2009,
Pubmed
Mitani-Ueno,
The aromatic/arginine selectivity filter of NIP aquaporins plays a critical role in substrate selectivity for silicon, boron, and arsenic.
2011,
Pubmed
,
Xenbase
Otto,
Aquaporin tetramer composition modifies the function of tobacco aquaporins.
2010,
Pubmed
Peng,
Overexpression of a Panax ginseng tonoplast aquaporin alters salt tolerance, drought tolerance and cold acclimation ability in transgenic Arabidopsis plants.
2007,
Pubmed
Romero,
Cloning and functional expression of rNBC, an electrogenic Na(+)-HCO3- cotransporter from rat kidney.
1998,
Pubmed
,
Xenbase
Romero,
Expression cloning using Xenopus laevis oocytes.
1998,
Pubmed
,
Xenbase
Ruiz-Lozano,
Regulation by arbuscular mycorrhizae of the integrated physiological response to salinity in plants: new challenges in physiological and molecular studies.
2012,
Pubmed
Sade,
Improving plant stress tolerance and yield production: is the tonoplast aquaporin SlTIP2;2 a key to isohydric to anisohydric conversion?
2009,
Pubmed
Sakurai,
Identification of 33 rice aquaporin genes and analysis of their expression and function.
2005,
Pubmed
Schnurbusch,
Boron toxicity tolerance in barley through reduced expression of the multifunctional aquaporin HvNIP2;1.
2010,
Pubmed
,
Xenbase
Smart,
MIP genes are down-regulated under drought stress in Nicotiana glauca.
2001,
Pubmed
Soto,
New insight into the evolution of aquaporins from flowering plants and vertebrates: orthologous identification and functional transfer is possible.
2012,
Pubmed
Taji,
Comparative genomics in salt tolerance between Arabidopsis and aRabidopsis-related halophyte salt cress using Arabidopsis microarray.
2004,
Pubmed
Taji,
Large-scale collection and annotation of full-length enriched cDNAs from a model halophyte, Thellungiella halophila.
2008,
Pubmed
Tamura,
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.
2007,
Pubmed
Taulavuori,
Comparison of two methods used to analyse lipid peroxidation from Vaccinium myrtillus (L.) during snow removal, reacclimation and cold acclimation.
2001,
Pubmed
Uehlein,
The tobacco aquaporin NtAQP1 is a membrane CO2 pore with physiological functions.
2003,
Pubmed
,
Xenbase
Uehlein,
Function of Nicotiana tabacum aquaporins as chloroplast gas pores challenges the concept of membrane CO2 permeability.
2008,
Pubmed
Volkov,
Thellungiella halophila, a salt-tolerant relative of Arabidopsis thaliana, has specific root ion-channel features supporting K+/Na+ homeostasis under salinity stress.
2006,
Pubmed
Wang,
SsTypA1, a chloroplast-specific TypA/BipA-type GTPase from the halophytic plant Suaeda salsa, plays a role in oxidative stress tolerance.
2008,
Pubmed
Wang,
A novel Glycine soja tonoplast intrinsic protein gene responds to abiotic stress and depresses salt and dehydration tolerance in transgenic Arabidopsis thaliana.
2011,
Pubmed
Wu,
Insights into salt tolerance from the genome of Thellungiella salsuginea.
2012,
Pubmed
Yamaguchi,
Developing salt-tolerant crop plants: challenges and opportunities.
2005,
Pubmed
Yool,
Structure, function and translational relevance of aquaporin dual water and ion channels.
2012,
Pubmed
Yu,
Water relations and an expression analysis of plasma membrane intrinsic proteins in sensitive and tolerant rice during chilling and recovery.
2006,
Pubmed
Zhang,
Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder.
1991,
Pubmed
,
Xenbase
Zhao,
Involvement of silicon influx transporter OsNIP2;1 in selenite uptake in rice.
2010,
Pubmed
Zhu,
Regulation of ion homeostasis under salt stress.
2003,
Pubmed
Zipor,
Do vacuolar peroxidases act as plant caretakers?
2013,
Pubmed