Bharate SS , Bharate SB .

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Andersson, TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH. 2004, Pubmed
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Behrendt, Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. 2004, Pubmed
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Brauchi, Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8. 2004, Pubmed
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De Petrocellis, Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. 2011, Pubmed
De Petrocellis, Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. 2008, Pubmed
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Harteneck, Synthetic modulators of TRP channel activity. 2011, Pubmed
Hatem, Psychophysical study of the effects of topical application of menthol in healthy volunteers. 2006, Pubmed
Hiserodt, Identification of monomenthyl succinate, monomenthyl glutarate, and dimenthyl glutarate in nature by high performance liquid chromatography-tandem mass spectrometry. 2004, Pubmed
Hui, Biophysical properties of menthol-activated cold receptor TRPM8 channels. 2005, Pubmed
Jiang, Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1. 2011, Pubmed
Jordt, Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. 2004, Pubmed
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Karashima, TRPA1 acts as a cold sensor in vitro and in vivo. 2009, Pubmed
Lashinger, AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome. 2008, Pubmed
Latorre, A cool channel in cold transduction. 2011, Pubmed
Lehen'kyi, Oncogenic TRP channels. 2011, Pubmed
Levine, TRP channels: targets for the relief of pain. 2007, Pubmed
Li, Transient receptor potential (TRP) channels as potential drug targets in respiratory disease. 2003, Pubmed
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Liu, Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate. 2005, Pubmed , Xenbase
Liu, TRPM8 in health and disease: cold sensing and beyond. 2011, Pubmed
Lumpkin, Mechanisms of sensory transduction in the skin. 2007, Pubmed
Ma, Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. 2008, Pubmed , Xenbase
Macpherson, An ion channel essential for sensing chemical damage. 2007, Pubmed
Macpherson, More than cool: promiscuous relationships of menthol and other sensory compounds. 2006, Pubmed
Matta, Voltage is a partial activator of rat thermosensitive TRP channels. 2007, Pubmed
McKemy, Identification of a cold receptor reveals a general role for TRP channels in thermosensation. 2002, Pubmed , Xenbase
McKemy, How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation. 2005, Pubmed
Moran, Transient receptor potential channels as therapeutic targets. 2011, Pubmed
Mukerji, Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. 2006, Pubmed
Mälkiä, The emerging pharmacology of TRPM8 channels: hidden therapeutic potential underneath a cold surface. 2011, Pubmed
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Numazaki, Nociception and TRP Channels. 2004, Pubmed
Ortar, (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels. 2010, Pubmed
Ottinger, Systematic studies on structure and physiological activity of cyclic alpha-keto enamines, a novel class of "cooling" compounds. 2001, Pubmed
Ottinger, Characterization of natural "cooling" compounds formed from glucose and l-proline in dark malt by application of taste dilution analysis. 2001, Pubmed
Park, Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain. 2006, Pubmed
Patapoutian, TRP channels and thermosensation. 2005, Pubmed
Penuelas, Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine. 2007, Pubmed
Prevarskaya, TRP channels in cancer. 2007, Pubmed
Reid, A system for applying rapid warming or cooling stimuli to cells during patch clamp recording or ion imaging. 2001, Pubmed
Reid, ThermoTRP channels and cold sensing: what are they really up to? 2005, Pubmed
Reid, Physiology. Cold current in thermoreceptive neurons. 2001, Pubmed
Reid, Ion channels activated by cold and menthol in cultured rat dorsal root ganglion neurones. 2002, Pubmed
Rohács, PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. 2005, Pubmed
Sherkheli, Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship. 2010, Pubmed , Xenbase
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Story, The emerging role of TRP channels in mechanisms of temperature and pain sensation. 2006, Pubmed
Story, ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. 2003, Pubmed
Tai, TRPA1: the central molecule for chemical sensing in pain pathway? 2008, Pubmed
Thebault, Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells. 2005, Pubmed
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Viana, TRPA1 modulators in preclinical development. 2009, Pubmed
Viana, Specificity of cold thermotransduction is determined by differential ionic channel expression. 2002, Pubmed
Voets, The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. 2004, Pubmed
Wasner, Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors. 2004, Pubmed
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Weil, Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8. 2005, Pubmed
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Wetsel, Sensing hot and cold with TRP channels. 2011, Pubmed
Xiao, Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. 2008, Pubmed
Yamamura, TRPM8 activation suppresses cellular viability in human melanoma. 2008, Pubmed
Yudin, Regulation of TRPM8 channel activity. 2012, Pubmed
Zhang, Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. 2004, Pubmed
Zhang, A-type GABA receptor as a central target of TRPM8 agonist menthol. 2008, Pubmed
Zhang, TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function? 2006, Pubmed