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XB-ART-4561
J Am Chem Soc 2003 Oct 22;12542:12668-9. doi: 10.1021/ja036155z.
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Protein surface recognition by rational design: nanomolar ligands for potassium channels.

Gradl SN , Felix JP , Isacoff EY , Garcia ML , Trauner D .


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The rational design and development of four-fold symmetrical ligands for potassium channels is described.

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References [+] :
Coghlan, Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress. 2001, Pubmed