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XB-ART-4527
Trends Cell Biol 2003 Nov 01;1311:547-50. doi: 10.1016/j.tcb.2003.09.006.
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Stu2p and XMAP215: turncoat microtubule-associated proteins?

Popov AV , Karsenti E .


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The dynamics of microtubule-based (MT) cytoskeletons are controlled by a variety of accessory proteins: microtubule-associated proteins (MAPs), which usually stabilize MTs, and microtubule-destabilizers. Two related MAPs, XMAP215 and Stu2p, are known to stabilize MTs. However, recent studies report that these proteins have a MT-destabilizing function as well. Here we discuss the implications of these reports.

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Species referenced: Xenopus
Genes referenced: ckap5