Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
J Anat
2010 Mar 01;2163:397-406. doi: 10.1111/j.1469-7580.2009.01191.x.
Show Gene links
Show Anatomy links
Mast cells in the amphibian brain during development.
Pinelli C
,
Santillo A
,
Baccari GC
,
Monteforte R
,
Rastogi RK
.
???displayArticle.abstract???
This is the first descriptive study of ontogenesis and anatomical distribution of mast cells in the developing brain of three different amphibian species. In the toad and the green frog, mast cells are preferentially located in: (i) the meningeal lining (pia mater), (ii) the choroid plexuses, both anterior and posterior, and (iii) the neuropil, in close association with the epithelial cell lining of blood vessels. It is only in the perennially aquatic African clawed frog that mast cells never appear inside brain ventricles and within the neuropil. Mast cells first become identifiable in brain of different species in different stages of development. While there are differences in the number of mast cells in different species at different stages of development, the number nearly doubles in all three species during the transition from pro-metamorphic stage of larval development to the peak of metamorphic climax. Furthermore, the number of mast cells is comparatively higher in the toad and remarkably lower in the fully aquatic Xenopus laevis, in which species the first appearance of identifiable mast cells during larval development occurs much later than in equivalent stages of development of the toad and the green frog. The secretory nature of mast cells can be assumed by the presence of cytoplasmic granules, which may show species-specific texture. Further experimental analyses are required to unveil the usefulness of mast cells in the amphibian brain.
Andrew,
The embryonic origin of connective tissue mast cells.
1987, Pubmed
Andrew,
The embryonic origin of connective tissue mast cells.
1987,
Pubmed
Baccari,
Thyroid status can influence brain mast cell population.
2009,
Pubmed
Baccari,
Induced maturation of frog mast cells by nerve growth factor during ontogenesis.
2003,
Pubmed
Chieffi Baccari,
In situ characterization of mast cells in the frog Rana esculenta.
1998,
Pubmed
Di Nardo,
Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin.
2008,
Pubmed
Esposito,
Mast cells in Wallerian degeneration: morphologic and ultrastructural changes.
2002,
Pubmed
Galli,
The two faces of the mast cell.
1996,
Pubmed
Galli,
New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity.
1990,
Pubmed
Irani,
Human mast cell heterogeneity.
1994,
Pubmed
Khalil,
Brain mast cell relationship to neurovasculature during development.
2007,
Pubmed
Lambracht-Hall,
Migration of mast cells in the developing rat brain.
1990,
Pubmed
Metcalfe,
Mast cells.
1997,
Pubmed
Michaloudi,
Developmental changes of mast cell populations in the cerebral meninges of the rat.
2007,
Pubmed
Minucci,
17 beta-estradiol effects on mast cell number and spermatogonial mitotic index in the testis of the frog, Rana esculenta.
1997,
Pubmed
Patella,
HIV-1 gp120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE.
2000,
Pubmed
Pinelli,
Distribution of FMRFamide-like immunoreactivity in the amphibian brain: comparative analysis.
1999,
Pubmed
Reite,
Inflammatory cells of teleostean fish: a review focusing on mast cells/eosinophilic granule cells and rodlet cells.
2006,
Pubmed
Silver,
Mast cells in the brain: evidence and functional significance.
1996,
Pubmed
Theoharides,
Mast cells: the immune gate to the brain.
1990,
Pubmed
Tsai,
The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype.
1991,
Pubmed
Yong,
The mast cell: origin, morphology, distribution, and function.
1997,
Pubmed
Zhuang,
Brain mast cell degranulation regulates blood-brain barrier.
1996,
Pubmed
Zhuang,
Mast cell number and maturation in the central nervous system: influence of tissue type, location and exposure to steroid hormones.
1997,
Pubmed
Zhuang,
Distribution and local differentiation of mast cells in the parenchyma of the forebrain.
1999,
Pubmed