Somasekharan S , Brandt R , Iwamoto T , Tomich JM , Schultz BD .

GM 066620 NIGMS NIH HHS , GM 074096 NIGMS NIH HHS

Acharya, Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. 2004, Pubmed

Acharya, Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. 2004, Pubmed
Anderson, Tight junctions and the molecular basis for regulation of paracellular permeability. 1995, Pubmed
Bell, Effects of phospholipid surface charge on ion conduction in the K+ channel of sarcoplasmic reticulum. 1984, Pubmed
Broughman, NH(2)-terminal modification of a channel-forming peptide increases capacity for epithelial anion secretion. 2001, Pubmed
Broughman, Channel-forming peptide modulates transepithelial electrical conductance and solute permeability. 2004, Pubmed , Xenbase
Broughman, Structural implications of placing cationic residues at either the NH2- or COOH-terminus in a pore-forming synthetic peptide. 2002, Pubmed
Broughman, Distinct structural elements that direct solution aggregation and membrane assembly in the channel-forming peptide M2GlyR. 2002, Pubmed
Carlin, PVD9902, a porcine vas deferens epithelial cell line that exhibits neurotransmitter-stimulated anion secretion and expresses numerous HCO3(-) transporters. 2006, Pubmed
Chung, A 22-amino acid synthetic peptide corresponding to the second extracellular loop of rat occludin perturbs the blood-testis barrier and disrupts spermatogenesis reversibly in vivo. 2001, Pubmed
Devor, Modulation of Cl- secretion by benzimidazolones. II. Coordinate regulation of apical GCl and basolateral GK. 1996, Pubmed
Devor, Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel. 1996, Pubmed
Edward, Predicted permeability of the cornea to topical drugs. 2001, Pubmed
Everett, Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. 2006, Pubmed
Fasano, Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro. 1995, Pubmed
Fasano, Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model. 1997, Pubmed
Fasano, Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin. 2000, Pubmed
Furuse, Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. 2001, Pubmed
Furuse, Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. 1996, Pubmed
González, Non-invasive routes for insulin administration: current state and perspectives. 2006, Pubmed
Heiskala, The roles of claudin superfamily proteins in paracellular transport. 2001, Pubmed
Kondoh, Progress in absorption enhancers based on tight junction. 2007, Pubmed
Lacaz-Vieira, Small synthetic peptides homologous to segments of the first external loop of occludin impair tight junction resealing. 1999, Pubmed
Lin, Electrophysiologic properties of channels induced by Abeta25-35 in planar lipid bilayers. 2002, Pubmed
McCarthy, Occludin is a functional component of the tight junction. 1996, Pubmed
Peppas, Hydrogels for oral delivery of therapeutic proteins. 2004, Pubmed
Schneeberger, The tight junction: a multifunctional complex. 2004, Pubmed
Shen, Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion. 1994, Pubmed
Spring, Routes and mechanism of fluid transport by epithelia. 1998, Pubmed
Spring, Size and shape of the lateral intercellular spaces in a living epithelium. 1978, Pubmed
Tavelin, A new principle for tight junction modulation based on occludin peptides. 2003, Pubmed
Thompson, Leucine enkephalin effects on paracellular and transcellular permeation pathways across brain microvessel endothelial cell monolayers. 1994, Pubmed
Tomich, Aqueous solubilization of transmembrane peptide sequences with retention of membrane insertion and function. 1998, Pubmed
Torchilin, Drug targeting. 2000, Pubmed
Türker, Nasal route and drug delivery systems. 2004, Pubmed
Wallace, A synthetic peptide derived from glycine-gated Cl- channel induces transepithelial Cl- and fluid secretion. 1997, Pubmed
Wong, A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. 1997, Pubmed , Xenbase
Zhang, Model of transient drug diffusion across cornea. 2004, Pubmed