XB-ART-37406
Curr Biol
2004 Jul 27;1414:R575-7. doi: 10.1016/j.cub.2004.07.017.
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Comparative genomics: prediction of the ciliary and basal body proteome.
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Defects in mammalian cilia lead to a range of diseases, but our understanding of the composition of these organelles and of the basal bodies from which they arise is limited. Two recent studies used comparative genomics to predict the ciliary and basal body proteomes, providing datasets that are rich sources of human disease gene candidates.
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References :
Marshall,
Human cilia proteome contains homolog of zebrafish polycystic kidney disease gene qilin.
2004, Pubmed