XB-ART-3651
Crit Rev Eukaryot Gene Expr
2004 Jan 01;141-2:79-88.
Show Gene links
Show Anatomy links
Chromatin domains and territories: flexibly rigid.
???displayArticle.abstract???
The nucleus is a highly organized solid-state system, rigid and flexible at the same time, where enzymes are organized in complex processing factories. This is achieved by the organization of nuclear DNA into territories and domains, which allow compartmentalization and compaction without sacrificing accessibility. The present review discusses the implications of the organization of chromosomal domains and territories in development and carcinogenesis.
???displayArticle.pubmedLink??? 15104529
???displayArticle.link??? Crit Rev Eukaryot Gene Expr