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XB-ART-33281
Science 1973 Jan 05;1794068:86-8.
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Photoreactivation of ultraviolet-induced chromosomal aberrations.

Griggs HG , Bender MA .


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Ultraviolet induces only chromatid-type aberrations in synchronized G(1) V-79 Chinese hamster and A8W243 Xenopus tissue culture cells. Posttreatment with white light prevents expression of most potential aberrations in the A8 toad cell, which possesses a photoreactivation enzyme. We conclude that the major ultraviolet-induced DNA lesion leading to chromosomal aberrations is the pyrimidine dimer.

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