Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-31997
Philos Trans R Soc Lond B Biol Sci 1978 May 11;283997:319-24. doi: 10.1098/rstb.1978.0031.
Show Gene links Show Anatomy links

Aspects of the regulation of histone genes.

Birnstiel ML , Kressmann A , Schaffner W , Portmann R , Busslinger M .


???displayArticle.abstract???
Sequencing of cloned histone DNA of the sea urchin Psammechinus miliaris has confirmed the map of the histone genes obtained earlier by rather less refined techniques. Sequencing of spacer has revealed that it is unlikely to code for protein. Some interesting sequences in the prelude regions to the structural genes have been found. The technique of injecting DNA into the germinal vesicle of the Xenopus oocyte has been greatly simplified, so that now many of the parameters governing the transcription of the injected genes can be investigated. Some mRNA-like molecules appear when circular histone DNA is inserted into the oocyte nucleus. We are cautiously optimistic that the technique can be further developed and will provide a useful tool for the study of the molecular mechanisms governing the expression of structural genes coding for proteins.

???displayArticle.pubmedLink??? 26076
???displayArticle.link??? Philos Trans R Soc Lond B Biol Sci