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XB-ART-31952
Naunyn Schmiedebergs Arch Pharmacol 1978 Jul 01;3033:295-7.
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High affinity of carozolol for beta-adrenoceptors coupled to the adenylyl cyclase in ventricular myocardium of kitten and Xenopus laevis.

Morris TH , Birnbaumer L , Kaumann AJ .


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Catecholamine-induced stimulation of adenylyl cyclase in ventricular membranes of kitten and Xenopus laevis was antagonized competitively by carazolol. Apparent equilibrium constants ranging between 100-170 pM were estimated for the beta-adrenoceptor-carazolol complex.

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References [+] :
ARUNLAKSHANA, Some quantitative uses of drug antagonists. 1959, Pubmed