XB-ART-31952
Naunyn Schmiedebergs Arch Pharmacol
1978 Jul 01;3033:295-7.
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High affinity of carozolol for beta-adrenoceptors coupled to the adenylyl cyclase in ventricular myocardium of kitten and Xenopus laevis.
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Catecholamine-induced stimulation of adenylyl cyclase in ventricular membranes of kitten and Xenopus laevis was antagonized competitively by carazolol. Apparent equilibrium constants ranging between 100-170 pM were estimated for the beta-adrenoceptor-carazolol complex.
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ARUNLAKSHANA,
Some quantitative uses of drug antagonists.
1959, Pubmed