Can J Physiol Pharmacol 1979 Oct 01;5710:1182-6.

Unusual particle trajectories and structural arrangements in myelinated nerve fibers.

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Others have reported that axonally transported particles, which usually travel in a direction roughly parallel to the axis of the nerve fiber, may suddenly shift sideways as though changing tracks. Examples of this rare type of movement are shown for particles undergoing transport in myelinated axons of Xenopus laevis. An examination of the structure of axons from Xenopus showed that some microtubules, neurofilaments, and elements of endoplasmic reticulum may also exhibit marked deviations from the axial direction. It is concluded that it is not necessary to propose any mechanism for changing tracks in order to explain the particle motion.

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