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Hum Genet
1980 Jan 01;553:333-6. doi: 10.1007/bf00290213.
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Effects of temperature on sister chromatid exchanges.
Speit G
.
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The influence of temperature on sister chromatid exchanges was investigated, and the results are discussed in connection with factors possible involved in temperature-induced SCE-formation. Whereas the SCE frequency increased with increasing growth temperature in a cell line of Xenopus laevis (EAX), which permits the examination of great temperature differences, a Chinese hamster cell line (V-79) revealed a U-shaped temperature-response curve. In addition, it was found that cold treatment at 4 degrees C caused an induction of SCEs in the V-79 cell line. Different BrdU concentrations had no effect on the temperature-induced SCE frequencies and mitomycin C led to an induction of SCEs parallel to the base-line values at different temperatures.
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