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Arch Environ Contam Toxicol
1980 Jan 01;92:181-91. doi: 10.1007/bf01055373.
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Cytotoxic effects of sodium selenite on tadpoles (Xenopus laevis).
Browne C
,
Dumont JN
.
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The cytotoxic effects of sodium selenite on developing tadpoles (Xenopus laevis) were examined by scanning, light, and electron microscopy. Selenium exposure resulted in disorganization, vacuolization, and swelling of the outer layer of epithelial cells in the tadpoleepidermis. Examination of muscle cells in the somites revealed myofibril disorganization and cell degeneration. Mitochondria in both epithelial and muscle cells were swollen and showed loss of cristae. It is likely that sublethal exposures to selenium compounds result in cellular damage which could affect motility, and thus survival, over longer periods of time.
Browne,
Toxicity of selenium to developing Xenopus laevis embryos.
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