XB-ART-31162
C R Seances Acad Sci III
1981 Jan 05;2921:65-7.
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[Meiotic maturation of the ovocyte of Xenopus laevis : a 4-step mechanism].
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Microinjection of the pure inhibitor (1) of cAMP dependent protein kinases (1.5 muM) into Xenopus oocytes triggered 100% germinal vesicle break down (GVBD), faster than progesterone and slower than the maturation promoting factor (MPF). Cholera toxin does not block (I) induced maturation; however cycloheximide inhibits (I) but not MPF induced GVBD.
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Genes referenced: camp