XB-ART-3037
Neuron
2004 Sep 16;436:760-2. doi: 10.1016/j.neuron.2004.09.002.
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Steering growth cones with a CaMKII/calcineurin switch.
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Calcium can regulate and induce both attractive and repulsive turnings by growth cones. In this issue of Neuron, Wen et al. report that differential activations of CaMKII and calcineurin (CaN) act as the read out for distinct patterns of intracellular calcium signals and a switch between attraction and repulsion.
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Species referenced: Xenopus
Genes referenced: camk2g ppp3ca tbx2
References :
Wen,
A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidance.
2004, Pubmed,
Xenbase