Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-29831
J Immunogenet 1984 Feb 01;111:97-101.
Show Gene links Show Anatomy links

Genetic limits of thymic immunosuppression of anti-hapten antibody production in Xenopus laevis laevis, the South African clawed toad.

Ruben LN , James HS , Clothier RH , Balls M .


???displayArticle.abstract???
Thymic immunosuppression in adult Xenopus laevis laevis, the South African clawed toad, is antigen-dependent and antigen-specific, but it is not genetically restricted. In this report, we show that combination in vitro with a thymus from an immunized Xenopus laevis laevis can suppress antibody production to a hapten from spleen fragments, if the spleen fragments are derived from a subspecies of Xenopus laevis or a species of Xenopus which shares the same diploid chromosome number (2N = 36). Some aspects of the evolution of thymic immunosuppression are considered in the light of these results.

???displayArticle.pubmedLink??? 6707484

???displayArticle.grants??? [+]