XB-ART-29621
Mutat Res
1984 Aug 01;1281:25-9. doi: 10.1016/0027-5107(84)90043-5.
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Effect of caffeine on induced damage in cells of Xenopus laevis.
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Xenopus laevis cells were treated with mitomycin C and subsequently treated with caffeine during either the S- or G2-phase of the cell cycle. The frequency of induced chromatid exchanges was especially increased by caffeine posttreatment during the S-phase. This increase took place at the expense of the frequency of isochromatid breaks, which was reduced, both when the caffeine posttreatment was given during the S- and G2-phase.
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