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XB-ART-29282
Neurosci Lett 1985 Mar 15;542-3:179-84. doi: 10.1016/s0304-3940(85)80075-6.
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Acetylcholine-induced currents at plasma membrane of the frog oocyte.

Toselli M , Simoncini L , Taglietti V , Tanzi F .


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Although with remarkable variability, membrane permeability in Rana oocytes can be modified by application of acetylcholine. The experiments were carried out in voltage-clamp conditions. Like in Xenopus, the responses proved to be related to activation of muscarinic receptors operating membrane channels probably selective for Cl-. At differences with Xenopus, the net acetylcholine-induced current showed remarkable deviation from linearity, displaying outward-going rectification. Application of acetylcholine typically produced opening of membrane channels, while in late spring, we observed the opposite effect in several batches of oocytes.

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Species referenced: Xenopus
Genes referenced: trim9