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XB-ART-29257
Cell Differ 1985 Apr 01;162:109-17. doi: 10.1016/0045-6039(85)90524-x.
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Immunohistochemical distribution of the histone H1(0)/H5 variant in various tissues of adult Xenopus laevis.

Moorman AF , de Boer PA .


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The cellular distribution of the histone H1(0)/H5 variant has been examined immunohistochemically in various tissues of adult Xenopus laevis, using monoclonal antibodies against this variant that was isolated from erythrocyte nuclei. The H1(0)/H5 variant appears not to be erythrocyte-specific and appears to be present in all cell types of liver, stomach, and skin. In contrast, in oocyte nuclei the H1(0)/H5 variant cannot be detected, whereas they do contain H1; the nuclei of spermatogenic cells contain the H1(0)/H5 variant, but probably less than the somatic cells. In Xenopus no H1(0) variant distinct from H5 seems to occur and the H1(0)/H5 variant apparently may perform a functional role related to mammalian H1(0).

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