XB-ART-28859
Comp Biochem Physiol B
1986 Jan 01;853:649-58.
Show Gene links
Show Anatomy links
Comparative biochemical study of alkaline phosphatase isozymes in fish, amphibians, reptiles, birds and mammals.
???displayArticle.abstract???
Alkaline phosphatases from the liver, kidney and intestine in various vertebrates were strongly inhibited by beryllium, 2-mercaptoethanol, potassium cyanide and EDTA. The enzymes showed various sensitivities to the inhibition by zinc and to heat denaturation at 56 degrees C for 5 min at pH 7.0. The liver and kidney enzymes showed higher sensitivity to the inhibition by L-homoarginine than by L-phenylalanine. The intestinal enzymes in higher vertebrates were more sensitive to the inhibition by L-phenylalanine than by L-homoarginine, whereas the intestinal ones in lower vertebrates showed quite similar sensitivities to both amino acids.
???displayArticle.pubmedLink??? 3491728