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XB-ART-28550
Cell Differ 1986 Sep 01;192:89-96. doi: 10.1016/0045-6039(86)90065-5.
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Influence of cytochalasin B on oocyte maturation in Xenopus laevis.

Ryabova LV , Betina MI , Vassetzky SG .


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Cytochalasin B (CB) exerts an inhibiting effect on the formation, migration and anchoring in the cortex of the meiotic spindle in maturing Xenopus laevis oocytes. Regional sensitivity to CB (CB-sensitive zones) has been found in the oocytes which varies with reference to the stage of oocyte maturation at which CB is applied. Light and electron microscopy has shown that in these CB-sensitive zones the yolk and pigment granules, unlike the cortical ones, are displaced into the cytoplasm centripetally under the influence of CB.

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