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XB-ART-26633
Dev Biol 1989 Jul 17;4921-2:389-91.
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Thyroxine influences neuronal connectivity in the adult frog brain.

Hofmann MH , Michler A , Meyer DL .


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In contrast to results of earlier investigations the influence of thyroxine on CNS connectivity is not restricted to circum-metamorphic stages in frogs. Neuroanatomical findings in adult Xenopus treated with thyroxine reveal a spread of the ipsilateral retino-tectal projection. Sprouting fibers establish a tectal innervation pattern similar to the one found in primitive fish. The question arises, whether thyroxine also has morphogenetic effects in the mature CNS of other species.

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