XB-ART-25632
Neurosci Lett
1990 Sep 04;1171-2:134-9. doi: 10.1016/0304-3940(90)90132-s.
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Interspecies differences in the population of multiple glutamate receptors expressed in Xenopus oocytes after injection of guinea pig, mouse and rat forebrain mRNAs.
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Expression of multiple glutamatergic responses was compared in Xenopus oocytes several days after injection of poly(A)+ RNAs from guinea pig, mouse and rat forebrains. No difference either in the characteristics of each response or in the amplitude of N-methyl-D-aspartate response was observed between the oocytes injected with mRNA from different species. However, the average magnitudes of kainate (KA) and oscillatory quisqualate (QA) responses produced by guinea pig brain mRNA were 1/2 and 1/6 times, respectively, of those by rat brain mRNA. These results may reflect that the guinea pig forebrain contains smaller amounts of ionotropic KA and metabotropic QA receptors than the rat forebrain.
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