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XB-ART-24206
J Physiol Paris 1992 Jan 01;861-3:123-8. doi: 10.1016/s0928-4257(05)80016-6.
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Spiral waves and intracellular calcium signalling.

Lechleiter JD , Clapham DE .


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Confocal imaging of intracellular Ca2+ brings a new level of resolution to the study of hormonal control of intracellular Ca2+ release. This approach has demonstrated the existence of pulsatile circular and spiral waves of Ca+ release induced by receptor activation. The data obtained by confocal imaging support a new framework for understanding intracellular Ca2+ signalling. The goal of this chapter is to review our data on the complexity of intracellular Ca2+ release in Xenopus oocytes, introduce the concept of Ca2+ excitability as a model for Ca2+ release and discuss the implications for encoding intracellular signal information.

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???displayArticle.link??? J Physiol Paris