J Biol Chem 1992 Mar 15;2678:5044-7.

Isolation and characterization of a Xenopus cDNA which encodes a homeodomain highly homologous to Drosophila Distal-less.

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A novel homeobox gene of Xenopus was isolated from the ovary cDNA library. The homeodomain of the encoded protein was homologous to that of Drosophila Distal-less (Dll), and the gene was termed Xdll. The mRNA exists in a large amount in ovary, and in a small amount in testis, but was not detected in muscle, kidney, gut, and liver. The mRNA also occurs in a large amount in oocytes and is maintained in unfertilized eggs and cleavage stage embryos as a maternal mRNA at a low but distinctly detectable level. The amount of the mRNA per embryo increases gradually in later stages by zygotic expression. Embryo dissection experiment revealed that the transcript is abundant in the anterior region at the neurula stage, suggesting that Xdll may play a role in the establishment of the structures in the anterior part of the embryo.

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???displayArticle.link??? J Biol Chem