XB-ART-23158
Biochem Biophys Res Commun
1992 Nov 30;1891:430-6.
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Modulation of transient type K channel cloned from rat heart.
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We have cloned a transient type K channel from rat heart (RH10) and coexpressed a metabotropic glutamate receptor (mGluR5) to study the functional modulation of RH10 coupled to the phosphatidylinositol (PI) hydrolysis. Stimulation of mGluR5 suppressed peak amplitude of RH10 current and affected voltage dependence of activation and inactivation of the channel.
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