XB-ART-22821
Biochem Biophys Res Commun
1993 Feb 15;1903:948-51.
Show Gene links
Show Anatomy links
Cloning and sequence analysis of hypothalamic cDNA encoding Xenopus preproneuropeptide Y.
???displayArticle.abstract???
Neuropeptide Y (NPY) consists of 36 amino acids and it constitutes one of the most conserved neuropeptides. Here we report the complete sequence of the first amphibian NPY precursor by cloning of a hypothalamic cDNA encoding Xenopus laevis preproNPY. The overall amino acid sequence identity between Xenopus and other known NPY precursor proteins ranges from 59% (fish) to 82% (chicken); a low degree of identity was found for the signal peptide sequence (32-75%) and for the carboxy-terminal peptide of NPY (CPON; 43-73%), while the NPY peptide sequence itself constitutes the most highly-conserved region (89-100%) within the preproNPY structure.
???displayArticle.pubmedLink??? 8439344
???displayArticle.link??? Biochem Biophys Res Commun
Species referenced: Xenopus laevis
Genes referenced: npy