Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-22695
Arch Environ Contam Toxicol 1993 Apr 01;243:359-64. doi: 10.1007/bf01128734.
Show Gene links Show Anatomy links

Effects of pentachlorophenol-contaminated food organisms on toxicity and bioaccumulation in the frog Xenopus laevis.

Schuytema GS , Nebeker AV , Peterson JA , Griffis WL .


???displayArticle.abstract???
Sub-adult African clawed frogs (Xenopus laevis) were fed pentachlorophenol (PCP)-injected mealworms containing 64.8 to 2604 ug of PCP per gram of worm for 27 days. There was no mortality and no significant bioaccumulation of PCP in the frogs. After three weeks, frogs fed 2,604 micrograms/g of PCP ceased eating. The no observed adverse effects level (NOAEL) based on significantly reduced food consumption (PCP-injected mealworms) was 638 micrograms/g. This corresponded to a NOAEL based on PCP intake of about 8 micrograms PCP/g frog/day. A toxicity threshold model estimated that about 800 micrograms/L of waterborne PCP may be a threshold for adverse effects in Xenopus or similar amphibians. Further study is needed to verify threshold estimates.

???displayArticle.pubmedLink??? 8470935
???displayArticle.link??? Arch Environ Contam Toxicol



References [+] :
Bevenue, Pentachlorophenol: a discussion of its properties and its occurrence as a residue in human and animal tissues. 1967, Pubmed