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XB-ART-22225
Neurosci Lett 1993 Sep 03;1591-2:183-6. doi: 10.1016/0304-3940(93)90829-a.
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Cloning and expression of a glutamate transporter from mouse brain.

Tanaka K .


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A complementary DNA clone encoding a transporter for glutamate has been isolated from mouse brain, and its functional properties have been examined in Xenopus oocytes. The transporter displays high affinity for glutamate (Km = 72 microM) and is dependent on external Na+. The cDNA sequence predicts a protein of 543 amino acids with 6 potential transmembrane domains. Northern blot analysis indicates the mRNA encoding the glutamate transporter is expressed both in the brain and in peripheral tissues.

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