XB-ART-21704
J Comput Biol
1994 Jan 01;11:51-64.
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Constructing aligned sequence blocks.
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This paper presents an efficient method for constructing aligned blocks (i.e., gap-free multiple alignments) from a set of pairwise alignments. The method is more sensitive than some earlier block-constructing methods for detecting conserved sequence regions. The technique is applied to analyze conserved regions in protein prenyltransferases and to detect regulatory elements in the 5' flank of the beta-globin gene.
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Species referenced: Xenopus