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XB-ART-20744
Sheng Li Xue Bao 1994 Oct 01;465:417-26.
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[Glutamate receptor and GABA receptor expressed in amphibian oocytes after injection of chicken retina mRNA].

Zhu X , Zhu H , Bao YD .


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The glutamate receptor and GABA receptor of chicken retina were studied with the expression system of amphibian oocyte. Some important results were obtained: L-glutamate, kainate, AMPA and quisqualate could all induce rapid and smooth depolarizing currents in oocytes. NMDA, L-AP4, trans-ACPD and L-aspartate had no effects. The antagonism of kainate response by AMPA and quisqualate was found, and it seemed that AMPA, quisqualate and KA could act on the same receptor. Comparing the responses to L-Glu and NMDA, it was found that the mRNA abundance of metabotropic glutamate receptor and NMDA receptor in chicken retina was much lower than that of chicken brain. The GABA receptor in chicken retina was very different from that of bovine retina. And although about 10% of the GABA response was insensitive to bicuculline, but most GABA receptors in chicken retina were proved as GABAA receptors.

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Species referenced: Xenopus laevis
Genes referenced: gabarap