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XB-ART-20204
FEBS Lett 1995 Jan 09;3573:269-74.
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Novel assay for the influenza virus M2 channel activity.

Giffin K , Rader RK , Marino MH , Forgey RW .


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The influenza A M2 ion channel was expressed and activity characterized in Xenopus oocytes. Based on the activation properties of the channels, a high throughput, non-electrophysiological screening assay was developed in order to identify novel inhibitors of the channel. This will facilitate discovery of novel agents to treat influenza viral infections.

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