XB-ART-20068
FEBS Lett
1995 Feb 27;3602:191-3.
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mRNA encoding the translation initiation factor eIF-4E is expressed early in Xenopus embryogenesis.
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The translation initiation factor eIF-4E plays an important role in regulating the overall rate of translation in eukaryotic cells. To investigate the expression of eIF-4E itself, we characterized the eIF-4E mRNA expressed in Xenopus embryos. 5'-RACE was performed to determine the 5'-end of the mRNA and the result predicts isoforms differing at the amino-terminal end. Expression of the eIF-4E mRNA in Xenopus oocytes and embryos was examined by RT-PCR. Xenopus eIF-4E mRNA is produced during oogenesis and persists during the early stages of embryogenesis as a maternal mRNA.
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Species referenced: Xenopus laevis
Genes referenced: cyp26a1 eif4e eif4e1b
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