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XB-ART-19240
J Biol Chem 1995 Sep 29;27039:22665-8.
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The interaction of TFIIIA with specific RNA-DNA heteroduplexes.

Nightingale KP , Wolffe AP .


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We examine the association of transcription factor TFIIIA with RNA-DNA heteroduplexes containing sequences from the Xenopus borealis 5 S rRNA gene. Under conditions where TFIIIA selectively binds to 5 S rRNA or the internal control region of the 5 S rRNA gene, no specific association of TFIIIA with DNA-RNA heteroduplexes containing either strand of 5 S DNA could be detected. We discuss our results with respect to specific models of TFIIIA recognition of the internal control region and of DNA-RNA hybrids by zinc finger proteins.

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Species referenced: Xenopus
Genes referenced: gtf3a