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XB-ART-17354
Clin Exp Pharmacol Physiol 1996 Dec 01;2312:1062-7. doi: 10.1111/j.1440-1681.1996.tb01170.x.
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Dominant inhibition of intercellular communication by two chimeric connexins.

Goliger JA, Bruzzone R, White TW, Paul DL.


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1. The physiological significance of communication through gap junction channels has been difficult to assess because channel activity cannot be experimentally modulated in a specific manner. To address this problem we have constructed chimeric connexins that function as dominant-negative inhibitors of intercellular channel activity.

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