XB-ART-17308
Sheng Li Xue Bao
1996 Dec 01;486:587-9.
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[Repression of voltage gated K+ channel expressed in Xenopus oocytes after injection total RNA from carp retina by an antisense oligonucleotide].
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Injection of total RNA from carp retina induced the formation of a membrane K+ channel in Xenopus oocytes. We found an oligonucleotide complementary to the mRNA coding for a peptide fragment in the K+ channel of drosophila and mice could suppress the K+ channel current in a very specific manner. This provides important information for the cloning of this gene and for studying it's function.
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Species referenced: Xenopus laevis
Genes referenced: mindy3