XB-ART-16660
Curr Biol
1997 Apr 01;74:R212-5. doi: 10.1016/s0960-9822(06)00103-5.
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Embryonic asymmetry: left TGFbeta at the right time?
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Vertebrates have consistent differences between their left and right sides. In all species, nodal, a transforming growth factor beta superfamily signalling protein, is involved in a late step in the pathways that specify such asymmetry in the embryo. Earlier components seem not so well conserved.
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Species referenced: Xenopus
Genes referenced: acvr2a gdf1 lefty nodal shh snai1 tgfb1