Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Chromosoma
1997 Jun 01;1057-8:452-8. doi: 10.1007/bf02510482.
Show Gene links
Show Anatomy links
Small nucleolar RNAs and nucleolar proteins in Xenopus anucleolate embryos.
Crosio C
,
Campioni N
,
Cardinali B
,
Amaldi F
,
Pierandrei-Amaldi P
.
???displayArticle.abstract???
We investigated the presence and localization, in the cells of anucleolate mutant embryos of Xenopus laevis, of three representative small nucleolar RNAs (snoRNAs), U3, U15 and U17, and of two nucleolar proteins, nucleolin and fibrillarin. The levels of the three snoRNAs in the anucleolate mutant are the same as in normal embryos, in contrast to 5S RNA and ribosomal proteins. In situ hybridization showed that, in the absence of fully organized nucleoli, the three RNAs are diffusely distributed in the nucleus and partly associated with a number of small structures. Nucleolin and fibrillarin are also present in the anucleolate embryos as in normal embryos, although there is less nucleolin mRNA in the former. The two nucleolar proteins were localized by immunofluorescence microscopy. Fibrillarin, similar to its associated U3 and U15 snoRNAs, is diffusely distributed in the anucleolate nucleus and is partly associated with small structures, probably prenucleolar bodies and pseudonucleoli. Nucleolin also appears diffusely distributed in the nucleus with some spots of higher concentration, but with a different pattern with respect to fibrillarin.
BROWN,
ABSENCE OF RIBOSOMAL RNA SYNTHESIS IN THE ANUCLEOLATE MUTANT OF XENOPUS LAEVIS.
1964, Pubmed,
Xenbase
BROWN,
ABSENCE OF RIBOSOMAL RNA SYNTHESIS IN THE ANUCLEOLATE MUTANT OF XENOPUS LAEVIS.
1964,
Pubmed
,
Xenbase
Balakin,
The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions.
1996,
Pubmed
Baserga,
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.
1991,
Pubmed
Brown,
Gene linkage by RNA-DNA hybridization. I. Unique DNA sequences homologous to 4 s RNA, 5 s RNA and ribosomal RNA.
1968,
Pubmed
,
Xenbase
Brown,
The genes for ribosomal RNA and their transcription during amphibian development.
1967,
Pubmed
,
Xenbase
Caizergues-Ferrer,
Nucleolin from Xenopus laevis: cDNA cloning and expression during development.
1989,
Pubmed
,
Xenbase
Caizergues-Ferrer,
Developmental expression of fibrillarin and U3 snRNA in Xenopus laevis.
1991,
Pubmed
,
Xenbase
Cecconi,
U17XS8, a small nucleolar RNA with a 12 nt complementarity to 18S rRNA and coded by a sequence repeated in the six introns of Xenopus laevis ribosomal protein S8 gene.
1994,
Pubmed
,
Xenbase
ELSDALE,
A mutation that reduces nucleolar number in Xenopus laevis.
1958,
Pubmed
,
Xenbase
ESPER,
A STUDY OF THE DEVELOPMENTAL CYTOLOGY OF A MUTATION AFFECTING NUCLEOLI IN XENOPUS EMBRYOS.
1964,
Pubmed
,
Xenbase
Hay,
Fine structure of the nucleolus in normal and mutant Xenopus embryos.
1967,
Pubmed
,
Xenbase
Hughes,
Depletion of U3 small nucleolar RNA inhibits cleavage in the 5' external transcribed spacer of yeast pre-ribosomal RNA and impairs formation of 18S ribosomal RNA.
1991,
Pubmed
Jeppesen,
Nucleotide sequence determination and secondary structure of Xenopus U3 snRNA.
1988,
Pubmed
,
Xenbase
Kass,
The U3 small nucleolar ribonucleoprotein functions in the first step of preribosomal RNA processing.
1990,
Pubmed
Kiss-László,
Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs.
1996,
Pubmed
Lapeyre,
Molecular cloning of Xenopus fibrillarin, a conserved U3 small nuclear ribonucleoprotein recognized by antisera from humans with autoimmune disease.
1990,
Pubmed
,
Xenbase
Maxwell,
The small nucleolar RNAs.
1995,
Pubmed
Messmer,
Requirements for nuclear translocation and nucleolar accumulation of nucleolin of Xenopus laevis.
1993,
Pubmed
,
Xenbase
Miller,
Control of 5S RNA synthesis during early development of anucleolate and partial nucleolate mutants of Xenopus laevis.
1973,
Pubmed
,
Xenbase
Miller,
Metabolism of 5S RNA in the absence of ribosome production.
1974,
Pubmed
,
Xenbase
Nicoloso,
Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs.
1996,
Pubmed
Ochs,
Nucleologenesis: composition and fate of prenucleolar bodies.
1985,
Pubmed
Pellizzoni,
Different forms of U15 snoRNA are encoded in the introns of the ribosomal protein S1 gene of Xenopus laevis.
1994,
Pubmed
,
Xenbase
Pellizzoni,
A Xenopus laevis homologue of the La autoantigen binds the pyrimidine tract of the 5' UTR of ribosomal protein mRNAs in vitro: implication of a protein factor in complex formation.
1996,
Pubmed
,
Xenbase
Pieler,
Point mutational analysis of the Xenopus laevis 5S gene promoter.
1985,
Pubmed
,
Xenbase
Pierandrei-Amaldi,
Expression of ribosomal-protein genes in Xenopus laevis development.
1982,
Pubmed
,
Xenbase
Pierandrei-Amaldi,
Aspects of regulation of ribosomal protein synthesis in Xenopus laevis. Review.
1994,
Pubmed
,
Xenbase
Pierandrei-Amaldi,
Ribosomal protein production in normal and anucleolate Xenopus embryos: regulation at the posttranscriptional and translational levels.
1985,
Pubmed
,
Xenbase
Probst,
Expression of sea urchin histone genes in the oocyte of Xenopus laevis.
1979,
Pubmed
,
Xenbase
Savino,
In vivo disruption of Xenopus U3 snRNA affects ribosomal RNA processing.
1990,
Pubmed
,
Xenbase
Scheer,
Functional and dynamic aspects of the mammalian nucleolus.
1990,
Pubmed
Steele,
Anucleolate frog embryos contain ribosomal DNA sequences and a nucleolar antigen.
1984,
Pubmed
,
Xenbase
Tashiro,
Structural analysis of ribosomal DNA homologues in nucleolus-less mutant of Xenopus laevis.
1986,
Pubmed
,
Xenbase
Wallace,
Ribosomal cistrons and the nucleolar organizer.
1966,
Pubmed
