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J Virol
1997 Nov 01;7111:8096-102. doi: 10.1128/JVI.71.11.8096-8102.1997.
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In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1.
Davey RA
,
Hamson CA
,
Healey JJ
,
Cunningham JM
.
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An amino-terminal portion of the Friend murine leukemia virus (MLV) envelope surface protein [SU, residues 1 to 236 [SU:(1-236)]] and its receptor, MCAT-1, were each purified from insect cells after expression by using recombinant baculoviruses. Friend SU:(1-236) bound specifically to Xenopus oocytes that expressed MCAT-1 with an affinity (Kd, 55 nM) similar to that of viral SU binding to permissive cells. Direct binding of Friend SU:(1-236) to purified MCAT-1 was observed in detergent and after reconstitution into liposomes. Analysis of binding demonstrated that MCAT-1 and Friend SU:(1-236) interact with a stoichiometry of near 1:1. These findings demonstrate that the amino-terminal domain from the SU of ecotropic murine retroviruses contains an MCAT-1 binding domain.
Albritton,
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection.
1989, Pubmed
Albritton,
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection.
1989,
Pubmed
Albritton,
Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses.
1993,
Pubmed
Bae,
Functional dissection of the Moloney murine leukemia virus envelope protein gp70.
1997,
Pubmed
Battini,
Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses.
1992,
Pubmed
Battini,
Receptor-binding domain of murine leukemia virus envelope glycoproteins.
1995,
Pubmed
Bullough,
Structure of influenza haemagglutinin at the pH of membrane fusion.
1994,
Pubmed
DeLarco,
Membrane receptors for murine leukemia viruses: characterization using the purified viral envelope glycoprotein, gp71.
1976,
Pubmed
Fass,
Retrovirus envelope domain at 1.7 angstrom resolution.
1996,
Pubmed
Goldstein,
The E5 oncoprotein of bovine papillomavirus binds to a 16 kd cellular protein.
1990,
Pubmed
Kim,
N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells.
1993,
Pubmed
,
Xenbase
Koch,
Nucleotide sequence of the envelope gene of Friend murine leukemia virus.
1983,
Pubmed
Laemmli,
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.
1970,
Pubmed
Linder,
Localization of the intrachain disulfide bonds of the envelope glycoprotein 71 from Friend murine leukemia virus.
1992,
Pubmed
MORRISON,
A FAST, SIMPLE AND RELIABLE METHOD FOR THE MICRODETERMINATION OF PHOSPHORUS IN BIOLOGICAL MATERIALS.
1964,
Pubmed
MacKrell,
Identification of a subdomain in the Moloney murine leukemia virus envelope protein involved in receptor binding.
1996,
Pubmed
Melton,
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.
1984,
Pubmed
Morgan,
Analysis of the functional and host range-determining regions of the murine ectropic and amphotropic retrovirus envelope proteins.
1993,
Pubmed
Ott,
Basis for receptor specificity of nonecotropic murine leukemia virus surface glycoprotein gp70SU.
1992,
Pubmed
Perkins,
Anemia and perinatal death result from loss of the murine ecotropic retrovirus receptor mCAT-1.
1997,
Pubmed
Pinter,
Ecotropic murine leukemia virus-induced fusion of murine cells.
1986,
Pubmed
Rein,
Different recombinant murine leukemia viruses use different cell surface receptors.
1984,
Pubmed
Wang,
Plasma membrane receptors for ecotropic murine retroviruses require a limiting accessory factor.
1991,
Pubmed
Wu,
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.
1996,
Pubmed
Zingler,
Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor.
1995,
Pubmed
van Zeijl,
A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.
1994,
Pubmed