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J Muscle Res Cell Motil
1998 Aug 01;196:675-87. doi: 10.1023/a:1005385232010.
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Calcium handling by the sarcoplasmic reticulum during oscillatory contractions of skinned skeletal muscle fibres.
Szentesi P
,
Zaremba R
,
Stienen GJ
.
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Isometric ATP consumption and force were investigated in mechanically skinned fibres from iliofibularismuscle of Xenopus laevis. Measurements were performed at different [Ca2+], in the presence and absence of caffeine (5 nM). In weakly Ca2+-buffered solutions without caffeine, spontaneous oscillations in force and ATPase activity occurred. The repetition frequency was [Ca2+]-and temperature-dependent. The Ca2+ threshold (+/- SEM) for the oscillations corresponded to a pCa of 6.5 +/- 0.1. The maximum ATP consumption associated with calcium uptake by the sarcoplasmic reticulum (SR) reached during the oscillations was similar to the activity under steady-state conditions at saturating calcium concentrations in the presence of caffeine. Maximum activity was reached when the force relaxation was almost complete. The calculated amount of Ca2+ taken up by the SR during a complete cycle corresponded to 5.4 +/ 0.4 mmol per litre cell volume. In strongly Ca2+-buffered solutions, caffeine enhanced the calcium sensitivity of the contractile apparatus and, at low calcium concentrations, SR Ca uptake. These results suggest that when the SR is heavily loaded by net Ca uptake, there is a massive calcium-induced calcium release. Subsequent net Ca uptake by the SR then gives rise to the periodic nature of the calcium transient.
Anazawa,
Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils. Microscopic measurement and analysis.
1992, Pubmed
Anazawa,
Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils. Microscopic measurement and analysis.
1992,
Pubmed
Armstrong,
Twitches in the presence of ethylene glycol bis( -aminoethyl ether)-N,N'-tetracetic acid.
1972,
Pubmed
Baylor,
Sarcoplasmic reticulum calcium release in frog skeletal muscle fibres estimated from Arsenazo III calcium transients.
1983,
Pubmed
Csernoch,
Microinjection of strong calcium buffers suppresses the peak of calcium release during depolarization in frog skeletal muscle fibers.
1993,
Pubmed
Fabiato,
Contractions induced by a calcium-triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.
1975,
Pubmed
Ford,
Intracellular calcium movements in skinned muscle fibres.
1972,
Pubmed
Ford,
Regenerative calcium release within muscle cells.
1970,
Pubmed
Ford,
Calcium uptake and force development by skinned muscle fibres in EGTA buffered solutions.
1972,
Pubmed
Fryer,
Total and sarcoplasmic reticulum calcium contents of skinned fibres from rat skeletal muscle.
1996,
Pubmed
Glyn,
Dependence of adenosine triphosphatase activity of rabbit psoas muscle fibres and myofibrils on substrate concentration.
1985,
Pubmed
Goldman,
Control of sarcomere length in skinned muscle fibres of Rana temporaria during mechanical transients.
1984,
Pubmed
Herrmann-Frank,
Regulation of the purified Ca2+ release channel/ryanodine receptor complex of skeletal muscle sarcoplasmic reticulum by luminal calcium.
1996,
Pubmed
Horiuti,
Mechanism of action of 2, 3-butanedione 2-monoxime on contraction of frog skeletal muscle fibres.
1988,
Pubmed
,
Xenbase
Horiuti,
Some properties of the contractile system and sarcoplasmic reticulum of skinned slow fibres from Xenopus muscle.
1986,
Pubmed
,
Xenbase
Jacquemond,
Voltage-gated and calcium-gated calcium release during depolarization of skeletal muscle fibers.
1991,
Pubmed
Jong,
Reduction of calcium inactivation of sarcoplasmic reticulum calcium release by fura-2 in voltage-clamped cut twitch fibers from frog muscle.
1993,
Pubmed
Klein,
Effects of caffeine on calcium release from the sarcoplasmic reticulum in frog skeletal muscle fibres.
1990,
Pubmed
Levy,
Ca2+ dependence of tension and ADP production in segments of chemically skinned muscle fibers.
1976,
Pubmed
Linke,
Spontaneous sarcomeric oscillations at intermediate activation levels in single isolated cardiac myofibrils.
1993,
Pubmed
Lyster,
Contractile activation and measurements of intracellular Ca2+ concentration in cane toad twitch fibres in the presence of 2,3-butanedione monoxime.
1995,
Pubmed
Melzer,
Time course of calcium release and removal in skeletal muscle fibers.
1984,
Pubmed
Melzer,
A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers.
1987,
Pubmed
Negretti,
The effects of inhibitors of sarcoplasmic reticulum function on the systolic Ca2+ transient in rat ventricular myocytes.
1993,
Pubmed
Okamura,
Spontaneous oscillatory contraction of sarcomeres in skeletal myofibrils.
1988,
Pubmed
Rousseau,
Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by caffeine and related compounds.
1988,
Pubmed
Shirokova,
Ca2+ release from the sarcoplasmic reticulum compared in amphibian and mammalian skeletal muscle.
1996,
Pubmed
Smith,
Theory and observation of spontaneous oscillatory contractions in skeletal myofibrils.
1994,
Pubmed
Steele,
Effects of 2,3-butanedione monoxime on sarcoplasmic reticulum of saponin-treated rat cardiac muscle.
1993,
Pubmed
Stienen,
Uptake and caffeine-induced release of calcium in fast muscle fibers of Xenopus laevis: effects of MgATP and P(i).
1993,
Pubmed
,
Xenbase
Stienen,
Depression of force by phosphate in skinned skeletal muscle fibers of the frog.
1990,
Pubmed
Stienen,
Myofibrillar ATPase activity in skinned human skeletal muscle fibres: fibre type and temperature dependence.
1996,
Pubmed
Stienen,
ATP utilization for calcium uptake and force production in skinned muscle fibres of Xenopus laevis.
1995,
Pubmed
,
Xenbase
Sun,
Molecular architecture of membranes involved in excitation-contraction coupling of cardiac muscle.
1995,
Pubmed
Wendt,
Effects of caffeine on Ca-activated force production in skinned cardiac and skeletal muscle fibres of the rat.
1983,
Pubmed