Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-12109
Cell Biol Int 1999 Jan 01;231:73-80. doi: 10.1006/cbir.1998.0318.
Show Gene links Show Anatomy links

Protein kinase C affects reformation of endothelial junctions in xenopus XTH-2 cells.

Werner NS , Meyer R , Achenbach F .


???displayArticle.abstract???
Endothelial cells can reversibly be forced to suppress the formation of endothelial junctions (EJ) by cultivation in a low calcium medium. The authors localized vinculin and cadherin as marker proteins of EJ and actin as a cytoskeletal component by fluorescence microscopy, and used this cell model to study the reformation of endothelial junctions under conditions of activation and inhibition of protein kinase C (PKC). Inhibition of PKC by H-7 leads to an acceleration of EJ reformation, while constitutive activation by TPA inhibits the reformation process.

???displayArticle.pubmedLink??? 10527549
???displayArticle.link??? Cell Biol Int


Species referenced: Xenopus
Genes referenced: actl6a